BDBM86253 CAS_100929-53-1::DAMGO::NSC_104742::US10836728, Compound DAMGO

SMILES CC(NC(=O)C(N)Cc1ccc(O)cc1)C(=O)NCC(=O)N(C)C(Cc1ccccc1)C(=O)NCCO

InChI Key InChIKey=HPZJMUBDEAMBFI-UHFFFAOYSA-N

Data  9 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 86253   

TargetMu-type opioid receptor(Human)
Mebias Discovery

US Patent
LigandPNGBDBM86253(CAS_100929-53-1 | NSC_104742 | DAMGO | US10836728,...)
Affinity DataEC50: <10nMAssay Description:G-protein signaling was measured via second messenger cAMP modulation. Detection of cAMP modulation was accomplished in the PathHunter human OPRM1 (&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
Go to US Patent

TargetBeta-arrestin-1(Human)
Mebias Discovery

US Patent
LigandPNGBDBM86253(CAS_100929-53-1 | NSC_104742 | DAMGO | US10836728,...)
Affinity DataEC50:  60nMAssay Description:The DISCOVERX PATHHUNTER β-Arrestin assay is used to measure β-arrestin-2 activity. The technology is based on Enzyme Fragment Complementat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2021
Entry Details
Go to US Patent

TargetMu-type opioid receptor(Human)
Mebias Discovery

US Patent
LigandPNGBDBM86253(CAS_100929-53-1 | NSC_104742 | DAMGO | US10836728,...)
Affinity DataKi:  1.18nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Cornell University

Curated by PDSP Ki Database
LigandPNGBDBM86253(CAS_100929-53-1 | NSC_104742 | DAMGO | US10836728,...)
Affinity DataKi:  1.22nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Innsbruck

Curated by PDSP Ki Database
LigandPNGBDBM86253(CAS_100929-53-1 | NSC_104742 | DAMGO | US10836728,...)
Affinity DataKi:  1.72nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
Cornell University

Curated by PDSP Ki Database
LigandPNGBDBM86253(CAS_100929-53-1 | NSC_104742 | DAMGO | US10836728,...)
Affinity DataKi:  2.83nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Innsbruck

Curated by PDSP Ki Database
LigandPNGBDBM86253(CAS_100929-53-1 | NSC_104742 | DAMGO | US10836728,...)
Affinity DataKi:  8.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Innsbruck

Curated by PDSP Ki Database
LigandPNGBDBM86253(CAS_100929-53-1 | NSC_104742 | DAMGO | US10836728,...)
Affinity DataKi:  32nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Cornell University

Curated by PDSP Ki Database
LigandPNGBDBM86253(CAS_100929-53-1 | NSC_104742 | DAMGO | US10836728,...)
Affinity DataKi:  213nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Mouse)
Mcgill University

Curated by PDSP Ki Database
LigandPNGBDBM86253(CAS_100929-53-1 | NSC_104742 | DAMGO | US10836728,...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2013
Entry Details
PubMed
TargetNociceptin receptor(Mouse)
Mcgill University

Curated by PDSP Ki Database
LigandPNGBDBM86253(CAS_100929-53-1 | NSC_104742 | DAMGO | US10836728,...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2013
Entry Details
PubMed