BDBM50255997 CHEMBL475600::D3RKN_93::N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(1H-pyrrol-2-yl)thieno[2,3-d]pyrimidin-4-amine

SMILES Fc1cccc(COc2ccc(Nc3ncnc4sc(cc34)-c3ccc[nH]3)cc2Cl)c1

InChI Key InChIKey=OHVZOXZMVPDEDV-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50255997   

TargetEpidermal growth factor receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50255997(N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(1H-pyr...)
Affinity DataIC50: 115nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50255997(N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(1H-pyr...)
Affinity DataIC50: 203nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
LigandPNGBDBM50255997(N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(1H-pyr...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2021More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

LigandPNGBDBM50255997(N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(1H-pyr...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2023More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R