BDBM50275550 2-(4-fluorophenyl)-6-methyl-3-(pyridin-4-yl)pyrazolo[1,5-a]pyridine::CHEMBL487581::D3RKN_68

SMILES Cc1ccc2c(c(nn2c1)c3ccc(cc3)F)c4ccncc4

InChI Key InChIKey=DLJKUEGEDDMTMQ-UHFFFAOYSA-N

Data  1 IC50  3 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50275550   

LigandChemical structure of BindingDB Monomer ID 50275550BDBM50275550(2-(4-fluorophenyl)-6-methyl-3-(pyridin-4-yl)pyrazo...)
Affinity DataKd:  20nMAssay Description:D3R2023More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetSerine/threonine protein kinase YCK2(Candida albicans (strain SC5314 / ATCC MYA-2876) (...)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275550BDBM50275550(2-(4-fluorophenyl)-6-methyl-3-(pyridin-4-yl)pyrazo...)
Affinity DataIC50: 29nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50275550BDBM50275550(2-(4-fluorophenyl)-6-methyl-3-(pyridin-4-yl)pyrazo...)
Affinity DataIC50: 44nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetSerine/threonine protein kinase YCK2(Candida albicans (strain SC5314 / ATCC MYA-2876) (...)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275550BDBM50275550(2-(4-fluorophenyl)-6-methyl-3-(pyridin-4-yl)pyrazo...)
Affinity DataIC50: 110nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50275550BDBM50275550(2-(4-fluorophenyl)-6-methyl-3-(pyridin-4-yl)pyrazo...)
Affinity DataIC50: 150nMAssay Description:Inhibition of GST-fused p38alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50275550BDBM50275550(2-(4-fluorophenyl)-6-methyl-3-(pyridin-4-yl)pyrazo...)
Affinity DataIC50: 170nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetCasein kinase I isoform delta(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275550BDBM50275550(2-(4-fluorophenyl)-6-methyl-3-(pyridin-4-yl)pyrazo...)
Affinity DataIC50: 230nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetCasein kinase I isoform epsilon(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275550BDBM50275550(2-(4-fluorophenyl)-6-methyl-3-(pyridin-4-yl)pyrazo...)
Affinity DataIC50: 780nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetCasein kinase I isoform alpha(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275550BDBM50275550(2-(4-fluorophenyl)-6-methyl-3-(pyridin-4-yl)pyrazo...)
Affinity DataIC50: 1.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
LigandChemical structure of BindingDB Monomer ID 50275550BDBM50275550(2-(4-fluorophenyl)-6-methyl-3-(pyridin-4-yl)pyrazo...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2021More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetTyrosine-protein kinase JAK2(Human)
D3R/Abbott

LigandChemical structure of BindingDB Monomer ID 50275550BDBM50275550(2-(4-fluorophenyl)-6-methyl-3-(pyridin-4-yl)pyrazo...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2022More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R