BDBM50105759 4-{5-(4-Fluoro-phenyl)-3-[1-(2,2,2-trifluoro-ethyl)-piperidin-4-yl]-3H-imidazol-4-yl}-pyrimidin-2-ylamine::CHEMBL95521::D3RKN_51

SMILES Nc1nccc(n1)-c1c(ncn1C1CCN(CC(F)(F)F)CC1)-c1ccc(F)cc1

InChI Key InChIKey=ZOLVPLVVVCAWCK-UHFFFAOYSA-N

Data  1 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50105759   

TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50105759(4-{5-(4-Fluoro-phenyl)-3-[1-(2,2,2-trifluoro-ethyl...)
Affinity DataIC50: 42nMAssay Description:Inhibition of p38 alpha kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50105759(4-{5-(4-Fluoro-phenyl)-3-[1-(2,2,2-trifluoro-ethyl...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2021More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetTyrosine-protein kinase JAK2(Human)
D3R/Abbott

LigandPNGBDBM50105759(4-{5-(4-Fluoro-phenyl)-3-[1-(2,2,2-trifluoro-ethyl...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2022More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
D3R/Abbott

LigandPNGBDBM50105759(4-{5-(4-Fluoro-phenyl)-3-[1-(2,2,2-trifluoro-ethyl...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R