BDBM50413871 CHEMBL473080::D3RKN_32

SMILES NCCNS(=O)(=O)c1ccc(cc1)-c1ccnc2[nH]ccc12

InChI Key InChIKey=HNQXYQNMPSACKT-UHFFFAOYSA-N

Data  4 IC50  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50413871   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50413871(CHEMBL473080 | D3RKN_32)
Affinity DataIC50: 40nMAssay Description:Inhibition of human IKKbeta using GST-IkappaBalpha as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50413871(CHEMBL473080 | D3RKN_32)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant IKK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
LigandPNGBDBM50413871(CHEMBL473080 | D3RKN_32)
Affinity DataIC50: 251nMAssay Description:Inhibition of human recombinant IKK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50413871(CHEMBL473080 | D3RKN_32)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant ROCK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
LigandPNGBDBM50413871(CHEMBL473080 | D3RKN_32)
Affinity DataKd:  2.90E+3nMAssay Description:D3R2021More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetTyrosine-protein kinase JAK2(Human)
D3R/Abbott

LigandPNGBDBM50413871(CHEMBL473080 | D3RKN_32)
Affinity DataKd:  100nMAssay Description:D3R2022More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

LigandPNGBDBM50413871(CHEMBL473080 | D3RKN_32)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2023More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetVenus kinase receptor 2(Blood fluke)
Imperial College London

Curated by ChEMBL
LigandPNGBDBM50413871(CHEMBL473080 | D3RKN_32)
Affinity DataKd:  2.53E+3nMAssay Description:Binding affinity to Schistosoma mansoni N-terminal His6-tagged full-length VKR2 kinase domain expressed in baculovirus infected Sf9 insect cells in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed