BDBM50292456 CHEMBL455633::Cularidine

SMILES COc1cc2C[C@@H]3N(C)CCc4ccc(O)c(Oc2cc1OC)c34

InChI Key InChIKey=ITGZZZYNPULRNZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50292456   

LigandPNGBDBM50292456(Cularidine | CHEMBL455633)
Affinity DataIC50: 4.12E+4nMAssay Description:Inhibition of dopamine transporter-mediated [3H]dopamine uptake in Wistar rat striatal synaptosomes by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50292456(Cularidine | CHEMBL455633)
Affinity DataIC50: 800nMAssay Description:Displacement of [3H]SCH-23390 from rat dopamine D1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50292456(Cularidine | CHEMBL455633)
Affinity DataIC50: 300nMAssay Description:Displacement of [3H]raclopride from rat dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50292456(Cularidine | CHEMBL455633)
Affinity DataIC50: 4.10E+4nMAssay Description:Displacement of [3H]DA from rat DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed