BDBM50088387 Clevidipine::Clevidipine butyrate::Cleviprex

SMILES CCCC(=O)OCOC(=O)C1=C(C)NC(C)=C(C1c1cccc(Cl)c1Cl)C(=O)OC

InChI Key InChIKey=KPBZROQVTHLCDU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50088387   

TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Guinea pig)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50088387(Clevidipine | Clevidipine butyrate | Cleviprex)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of L-type calcium channel measured using whole-cell patch clamp in guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Guinea pig)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50088387(Clevidipine | Clevidipine butyrate | Cleviprex)
Affinity DataIC50: 79nMAssay Description:Inhibition of L-type calcium channel measured using whole-cell patch clamp in guinea pig ventricular myocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50088387(Clevidipine | Clevidipine butyrate | Cleviprex)
Affinity DataIC50: 3.64E+4nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed