BDBM48532 2-butoxy-N-[2-(diethylamino)ethyl]-4-quinolinecarboxamide;hydrochloride::2-butoxy-N-[2-(diethylamino)ethyl]cinchoninamide;hydrochloride::2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide;hydrochloride::Cincain::Cinchocaine::DIBUCAINE HYDROCHLORIDE::Dibucaine::MLS000028429::Nupercainal::Nupercaine::SMR000058369::Sovcaine::cid_521951

SMILES CCCCOc1cc(C(=O)NCCN(CC)CC)c2ccccc2n1

InChI Key InChIKey=PUFQVTATUTYEAL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 48532   

LigandPNGBDBM48532(SMR000058369 | cid_521951 | DIBUCAINE HYDROCHLORID...)
Affinity DataIC50: 5.00E+4nMAssay Description:Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
LigandPNGBDBM48532(SMR000058369 | cid_521951 | DIBUCAINE HYDROCHLORID...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2018
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM48532(SMR000058369 | cid_521951 | DIBUCAINE HYDROCHLORID...)
Affinity DataIC50: 4.17E+4nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed