BDBM50241084 3'-Methoxyapigenin::4',5,7-trihydroxy-3'-methoxyflavone::5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-benzopyrone::5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one::5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one::CHEMBL214321::Chryseriol::Chrysoeriol::Chrysoeriol (26)::Luteolin 3'-methyl ether::cid_5280666

SMILES COc1cc(ccc1O)-c1cc(=O)c2c(O)cc(O)cc2o1

InChI Key InChIKey=SCZVLDHREVKTSH-UHFFFAOYSA-N

Data  10 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50241084   

LigandPNGBDBM50241084(Chrysoeriol | CHEMBL214321 | cid_5280666 | 5,7-dih...)
Affinity DataEC50:  1.75E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2011
Entry Details
PCBioAssay
TargetMitogen-activated protein kinase 14(Human)
Eberhard Karls University of Tuebingen

LigandPNGBDBM50241084(Chrysoeriol | CHEMBL214321 | cid_5280666 | 5,7-dih...)
Affinity DataIC50: 3.36E+4nMT: 2°CAssay Description:The p38alpha reaction was carried out by using kinase (12ng per well), ATP (100uM) and incubated for 60 min at 37 C. For the JNK3 assay, kinase (10n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Konkuk University

LigandPNGBDBM50241084(Chrysoeriol | CHEMBL214321 | cid_5280666 | 5,7-dih...)
Affinity DataIC50: 3.98E+3nMAssay Description:The kinase assay was performed using the EMD Millipore KinaseProfiler service assay protocol. Aurora B kinase was supplied by EMD Millipore Corp. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2015
Entry Details Article
PubMed
TargetMultidrug resistance-associated protein 1(Human)
The Hong Kong Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50241084(Chrysoeriol | CHEMBL214321 | cid_5280666 | 5,7-dih...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of MRP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 2(Human)
The Hong Kong Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50241084(Chrysoeriol | CHEMBL214321 | cid_5280666 | 5,7-dih...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of MRP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50241084(Chrysoeriol | CHEMBL214321 | cid_5280666 | 5,7-dih...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of cow milk xanthine oxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50241084(Chrysoeriol | CHEMBL214321 | cid_5280666 | 5,7-dih...)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of human CYP1A2 by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50241084(Chrysoeriol | CHEMBL214321 | cid_5280666 | 5,7-dih...)
Affinity DataIC50: 95nMAssay Description:Inhibition of human CYP1A1 by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50241084(Chrysoeriol | CHEMBL214321 | cid_5280666 | 5,7-dih...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human CYP1B1 by EROD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50241084(Chrysoeriol | CHEMBL214321 | cid_5280666 | 5,7-dih...)
Affinity DataIC50: 95nMAssay Description:Inhibition of recombinant human CYP1A1 expressed in supersomes using ethoxyresorufin as substrate preincubated for 5 mins followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50241084(Chrysoeriol | CHEMBL214321 | cid_5280666 | 5,7-dih...)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in supersomes using ethoxyresorufin as substrate preincubated for 5 mins followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2019
Entry Details Article
PubMed