BDBM91849 Chk1_125

SMILES COC(=O)Cc1ccc2c(c1)NC(=O)c3ccc(cc3N2)Nc4ccncc4

InChI Key InChIKey=UHXSMHRHMWNZNO-UHFFFAOYSA-N

Data  3 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 91849   

LigandPNGBDBM91849(Chk1_125)
Affinity DataIC50: 12nMAssay Description:Abbott Kinase Enzymatics_CHK1/289 CDC25c - IC50(uM) (IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2012
Entry Details PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM91849(Chk1_125)
Affinity DataKi:  10nMAssay Description:ChemBL affinity - Published Abbott papersMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2012
Entry Details PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM91849(Chk1_125)
Affinity DataKi:  10nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM91849(Chk1_125)
Affinity DataKi:  11.5nMAssay Description:33P-Radiometric_Method1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2017
Entry Details
D3R
PDB3D3D Structure (crystal)