BDBM50049572 1,3-benzodiazine::1,3-diazanaphthalene::5,6-benzopyrimidine::CHEMBL301359::Chinazolin::US11292789, Quinazoline::benzo[a]pyrimidine::phenmiazine::quinazoline

SMILES c1ccc2c(c1)cncn2

InChI Key InChIKey=JWVCLYRUEFBMGU-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50049572   

TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandBDBM50049572(quinazoline | 1,3-benzodiazine | 1,3-diazanaphthal...)Copy SMILESCopy InChI

Affinity DataIC50: 27nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
3/9/2005
Entry Details Article
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TargetGlucan 1,4-alpha-glucosidase(Shiitake mushroom)
Medicare Pharmaceuticals

US Patent

LigandBDBM50049572(quinazoline | 1,3-benzodiazine | 1,3-diazanaphthal...)Copy SMILESCopy InChI

Affinity DataIC50: 278nMAssay Description:Using the samples prepared according to Example 1 and Comparative Examples 2 and 3, inhibitory activity against α-glucosidase was evaluated to a...More data for this Ligand-Target Pair

Target InfoUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
7/21/2022
Entry Details
Copy Entry DOIGo to US Patent

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