BDBM50043798 (R)-2-Benzyloxycarbonylamino-3-phenyl-propionic acid::CHEMBL63865::Cbz-D-Phe

SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key InChIKey=RRONHWAVOYADJL-UHFFFAOYSA-N

Data  2 IC50  1 ITC

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043798   

TargetStromelysin-1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50043798(Cbz-D-Phe | CHEMBL63865 | (R)-2-Benzyloxycarbonyla...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of recombinant full length stromelysin (FLS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50043798(Cbz-D-Phe | CHEMBL63865 | (R)-2-Benzyloxycarbonyla...)
Affinity DataIC50: 5.00E+5nMAssay Description:In vitro inhibition of recombinant stromelysin catalytic domain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 50043798   

HostPNGBDBM36126(gamma-cyclodextrin)
Japan Science and Technology Agency

GuestPNGBDBM50043798(Cbz-D-Phe | CHEMBL63865 | (R)-2-Benzyloxycarbonyla...)
ITC DataΔG°: -3.06kcal/mole −TΔS°: -0.214kcal/mole ΔH°: -2.84kcal/mole logk: 175
pH: 6.9 T: 25.00°C