BDBM50184688 CHEMBL377236::Caulerpin

SMILES COC(=O)C1=C/c2c([nH]c3ccccc23)\C(=C/c2c\1[nH]c1ccccc21)C(=O)OC

InChI Key InChIKey=PVWALMHWUOWPPA-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50184688   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50184688(Caulerpin | CHEMBL377236)
Affinity DataIC50: 3.77E+3nMAssay Description:Inhibition of human PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50184688(Caulerpin | CHEMBL377236)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to IDO1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Panjab University

Curated by ChEMBL
LigandPNGBDBM50184688(Caulerpin | CHEMBL377236)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human IDO1 using L-tryptophan as substrate assessed as reduction in N-formyl kynurenine formation by measuring inhibition constant by U...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed