BDBM50111717 2-[3-(2-Fluoro-phenylmethanesulfonylamino)-2-oxo-2H-pyridin-1-yl]-N-((R)-1-formyl-4-guanidino-butyl)-acetamide::CHEMBL19599::CVS-2139

SMILES NC(=N)NCCC[C@@H](NC(=O)Cn1cccc(NS(=O)(=O)Cc2ccccc2F)c1=O)C(O)=O

InChI Key InChIKey=OFDAQIKHAJYTBV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50111717   

TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50111717(CVS-2139 | 2-[3-(2-Fluoro-phenylmethanesulfonylami...)
Affinity DataKi:  0.560nMAssay Description:In vitro inhibitory constant against human thrombin (FIIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50111717(CVS-2139 | 2-[3-(2-Fluoro-phenylmethanesulfonylami...)
Affinity DataKi:  21nMAssay Description:In vitro inhibitory constant against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50111717(CVS-2139 | 2-[3-(2-Fluoro-phenylmethanesulfonylami...)
Affinity DataKi:  192nMAssay Description:In vitro inhibitory constant against factor Xa (FXa) was testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed