BDBM7144 3-Benzamidoaminopyrazole deriv. 21::4-bromo-N-(5-cyclohexyl-1H-pyrazol-3-yl)benzamide::CHEMBL333382::CS5::N-(5-Cycloexyl-1H-pyrazol-3-yl)-4-bromobenzamide

SMILES Brc1ccc(cc1)C(=O)Nc1cc(n[nH]1)C1CCCCC1

InChI Key InChIKey=UCKVPBMWWJALAJ-UHFFFAOYSA-N

Data  2 IC50  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 7144   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Pharmacia Italia

LigandPNGBDBM7144(N-(5-Cycloexyl-1H-pyrazol-3-yl)-4-bromobenzamide |...)
Affinity DataIC50: 1.00E+3nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Csar

LigandPNGBDBM7144(N-(5-Cycloexyl-1H-pyrazol-3-yl)-4-bromobenzamide |...)
Affinity DataKd: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:ThermofluorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2012
Entry Details PubMed
TargetCyclin-dependent kinase 2(Human)
Csar

LigandPNGBDBM7144(N-(5-Cycloexyl-1H-pyrazol-3-yl)-4-bromobenzamide |...)
Affinity DataKd: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2012
Entry Details PubMed
TargetCyclin-dependent kinase 2(Human)
Csar

LigandPNGBDBM7144(N-(5-Cycloexyl-1H-pyrazol-3-yl)-4-bromobenzamide |...)
Affinity DataKd: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:OctetRedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2012
Entry Details PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Pharmacia Italia

LigandPNGBDBM7144(N-(5-Cycloexyl-1H-pyrazol-3-yl)-4-bromobenzamide |...)
Affinity DataKd: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2012
Entry Details PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Pharmacia Italia

LigandPNGBDBM7144(N-(5-Cycloexyl-1H-pyrazol-3-yl)-4-bromobenzamide |...)
Affinity DataKd: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:OctetRedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2012
Entry Details PubMed
TargetCyclin-dependent kinase 2(Human)
Csar

LigandPNGBDBM7144(N-(5-Cycloexyl-1H-pyrazol-3-yl)-4-bromobenzamide |...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2/Cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed