BDBM50284690 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2-yl)-vinyl]-benzyloxy}-phenyl)-2-methyl-1H-imidazo[4,5-c]pyridine::CHEMBL31714::CP-96021

SMILES Cc1nc2cnccc2n1-c1ccc(OCc2cccc(\C=C\c3nc4cc(F)ccc4s3)c2)cc1

InChI Key InChIKey=DXTYGLAQRALLEG-UHFFFAOYSA-N

Data  2 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50284690   

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetAdenosine receptor A1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetHistamine H1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSerotonin 2 (5-HT2) receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Beta adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]LTD4 from receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetPlatelet-activating factor receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50284690(CP-96021 | 1-(4-{3-[(E)-2-(5-Fluoro-benzothiazol-2...)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]ligand from platelet activating factor (PAF) receptor in rabbit plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article