BDBM50065965 5-Chloro-1H-indole-2-carboxylic acid ((1S,2R)-1-benzyl-2-dimethylcarbamoyl-2-hydroxy-ethyl)-amide::5-Chloro-1H-indole-2-carboxylic acid [2-((R)-dimethyl-carbamoyl)-2-hydroxy-1-((S)-phenylmethyl)-ethyl]-amide::CHEMBL319136::CP-91149

SMILES CN(C)C(=O)[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc2cc(Cl)ccc2[nH]1

InChI Key InChIKey=HINJNZFCMLSBCI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50065965   

TargetGlycogen phosphorylase, liver form(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50065965(5-Chloro-1H-indole-2-carboxylic acid [2-((R)-dimet...)
Affinity DataIC50: 110nMAssay Description:In vitro inhibitory activity against recombinant human liver glycogen phosphorylase a (rHLGPa) catalyzed release of phosphate from glucose-1-phosphat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycogen phosphorylase, liver form(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50065965(5-Chloro-1H-indole-2-carboxylic acid [2-((R)-dimet...)
Affinity DataIC50: 110nMAssay Description:Inhibitory concentration against glycogen phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycogen phosphorylase, liver form(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065965(5-Chloro-1H-indole-2-carboxylic acid [2-((R)-dimet...)
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against glycogen phosphorylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlycogen phosphorylase, liver form(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50065965(5-Chloro-1H-indole-2-carboxylic acid [2-((R)-dimet...)
Affinity DataIC50: 82nMAssay Description:Inhibition of human recombinant liver glycogen phosphorylase A expressed in baculovirus infected Sf9 insect cells assessed as release of phosphate fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2018
Entry Details Article
PubMed