BDBM50332607 9-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-2,3,4,4a,9,9a-hexahydro-1H-carbazole::CHEMBL463821::CP-352664

SMILES C1CCC2C(C1)N(c1ccccc21)c1ncnc2[nH]ccc12

InChI Key InChIKey=QKYQEWXQVQGDJR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50332607   

TargetTyrosine-protein kinase JAK1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332607(9-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-2,3,4,4a,9,9a-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-tagged human JAK1 catalytic domain expressed in Sf9 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50332607(9-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-2,3,4,4a,9,9a-...)
Affinity DataIC50: 210nMAssay Description:Inhibition of GST-tagged human JAK3 catalytic domain expressed in Sf9 cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed