BDBM50367033 COENZYME_A

SMILES CC(C)(CO[P@](=O)(O)O[P@@](=O)(O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)n2cnc3c2ncnc3N)O)OP(=O)(O)O)[C@H](C(=O)NCCC(=O)NCCS)O

InChI Key InChIKey=RGJOEKWQDUBAIZ-UHFFFAOYSA-N

Data  1 KI  3 IC50  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50367033   

TargetHistone acetyltransferase KAT5(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50367033(COENZYME_A)
Affinity DataIC50: 8.23E+4nMAssay Description:Inhibition of recombinant Tip60 (1-513) expressed in Escherichia coli BL21 (DE3) by liquid scintillationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50367033(COENZYME_A)
Affinity DataIC50: 4.59E+4nMAssay Description:Inhibition of recombinant p300More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50367033(COENZYME_A)
Affinity DataIC50: 4.19E+4nMAssay Description:Inhibition of PCAF HAT domain (493-658) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetN-alpha-acetyltransferase 50(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50367033(COENZYME_A)
Affinity DataKd:  156nMAssay Description:Binding affinity to full length human N-terminal His-tagged/GST-tagged Naa50 expressed in Escherichia coli BL21(DE3) cells in by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein phosphatase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50367033(COENZYME_A)
Affinity DataEC50:  1nMAssay Description:Activation of PPP5C (unknown origin) TPR domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCholine O-acetyltransferase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50367033(COENZYME_A)
Affinity DataKi:  7.50E+4nMAssay Description:Inhibition of choline acetyltransferase isolated from squid head gangliaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2012
Entry Details Article
PubMed