BDBM170149 (4aS,5aS,6S,12aR)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide::CMT-1

SMILES C[C@]1(O)[C@H]2C[C@H]3CC(=O)C(C(N)=O)=C(O)[C@@]3(O)C(=O)C2=C(O)c2c(O)cccc12

InChI Key InChIKey=XCCHQGIGHCRZOS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 170149   

Target72 kDa type IV collagenase(Human)
Nanjing University

LigandPNGBDBM170149((4aS,5aS,6S,12aR)-1,6,10,11,12a-pentahydroxy-6-met...)
Affinity DataIC50: 1.13E+3nMAssay Description:This esterase assay used 4-nitrophenylacetate as a substrate. Initially, the rhMMP-2 was diluted to 100 µg/mL with 1 mM APMA in assay buffer. Later, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed