BDBM50111440 4-(1-carbamoyl-4-methylpentanamide-2-yl-cyclopropylcarbamoyl)-4-{2-(6-chloro-1H-3-indolyl)-1-[1-{1-methyl-1-[1-(1-methylcarboxamido-2-phenylethylcarboxamido)-3-methylsulfanylpropylcarboxamido]ethylcarboxamido}-2-(4-methylphosphatephenyl)ethylcarboxamido]ethylcarboxamido}butanoic acid::Ac-Phe-Met-Aib-Pmp-6-Cl-Trp-Glu-Ac3c-Leu-NH2, GST-hdm2 binding peptide::CID44286587

SMILES CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(C)=O)C(=O)NC(C)(C)C(=O)N[C@@H](Cc1ccc(CP([O-])([O-])=O)cc1)C(=O)N[C@@H](Cc1c[nH]c2cc(Cl)ccc12)C(=O)N[C@@H](CCC(O)=O)C(=O)NC1(CC1)C(=O)N[C@@H](CC(C)C)C(N)=O

InChI Key InChIKey=FBKFDSUZBVDZIX-UHFFFAOYSA-L

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50111440   

TargetGlutathione S-transferase A2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50111440(Ac-Phe-Met-Aib-Pmp-6-Cl-Trp-Glu-Ac3c-Leu-NH2, GST-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of p53 binding to Glutathione S-transferase 2 (hdm2-GST)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50111440(Ac-Phe-Met-Aib-Pmp-6-Cl-Trp-Glu-Ac3c-Leu-NH2, GST-...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human GST-tagged MDM2 assessed as inhibition of binding to full length p53More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed