BDBM50422043 CHEMBL2062144::CI-988::PD-137342

SMILES C[C@@](Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)NC[C@H](NC(=O)CCC(O)=O)c1ccccc1

InChI Key

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50422043   

LigandPNGBDBM50422043(CI-988 | PD-137342 | CHEMBL2062144)
Affinity DataIC50: 1.70nMAssay Description:The concentration (nM) producing half-maximal inhibition of specific binding of [1251] Bolton Hunter CCK-8 to CCK receptors in the mouse cerebral cor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50422043(CI-988 | PD-137342 | CHEMBL2062144)
Affinity DataIC50: 4.30E+3nMAssay Description:The concentration (nM) producing half-maximal inhibition of specific binding of [1251] Bolton Hunter CCK-8 to CCK receptors in the rat pancreas (CCK-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details

LigandPNGBDBM50422043(CI-988 | PD-137342 | CHEMBL2062144)
Affinity DataIC50: 34nMAssay Description:In vitro inhibition of [125I]- Bolton Hunter CCK-8 binding to Cholecystokinin type B receptor in the mouse cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50422043(CI-988 | PD-137342 | CHEMBL2062144)
Affinity DataIC50: 3.10E+3nMAssay Description:In vitro inhibition of [125I]- Bolton Hunter CCK-8 to Cholecystokinin type A receptor in the rat pancreas.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50422043(CI-988 | PD-137342 | CHEMBL2062144)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor of rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50422043(CI-988 | PD-137342 | CHEMBL2062144)
Affinity DataIC50: 63nMAssay Description:Inhibition of [125I]CCK-8 to Cholecystokinin type B receptor in the mouse cerebral cortex.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article

LigandPNGBDBM50422043(CI-988 | PD-137342 | CHEMBL2062144)
Affinity DataKi:  62nMAssay Description:Cholecystokinin type B receptor binding assay performed on homogenized cerebral cortex from male mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2019
Entry Details Article
PubMed