BDBM50048299 4-Phenyl-1-((R)-3-phenyl-cyclohex-3-enylmethyl)-1,2,3,6-tetrahydro-pyridine::CHEMBL335545::CI-1007

SMILES C([C@@H]1CCC=C(C1)c1ccccc1)N1CCC(=CC1)c1ccccc1

InChI Key InChIKey=XBGWTWPYCTZIIE-UHFFFAOYSA-N

Data  11 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50048299   

TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50048299(CHEMBL335545 | 4-Phenyl-1-((R)-3-phenyl-cyclohex-3...)
Affinity DataIC50: 53nMAssay Description:In vitro inhibition of [3H]spiperone binding to Dopamine D2 receptor in rat striatum.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50048299(CHEMBL335545 | 4-Phenyl-1-((R)-3-phenyl-cyclohex-3...)
Affinity DataKi:  3.30nMAssay Description:Tested for binding affinity towards rat striatal D2 receptor using [3H]NPA as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048299(CHEMBL335545 | 4-Phenyl-1-((R)-3-phenyl-cyclohex-3...)
Affinity DataKi:  8.40nMAssay Description:Binding affinity towards human Dopamine receptor D2L evaluated using [3H]N-0437More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048299(CHEMBL335545 | 4-Phenyl-1-((R)-3-phenyl-cyclohex-3...)
Affinity DataKi:  16.6nMAssay Description:Binding affinity towards human Dopamine receptor D3 evaluated using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048299(CHEMBL335545 | 4-Phenyl-1-((R)-3-phenyl-cyclohex-3...)
Affinity DataKi:  16.6nMAssay Description:Compound was measured for its ability to compete with [3H]spiperone binding to the human Dopamine receptor D3 transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048299(CHEMBL335545 | 4-Phenyl-1-((R)-3-phenyl-cyclohex-3...)
Affinity DataKi:  17nMAssay Description:Tested for binding affinity towards human D3 receptor using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048299(CHEMBL335545 | 4-Phenyl-1-((R)-3-phenyl-cyclohex-3...)
Affinity DataKi:  25.5nMAssay Description:Binding affinity towards human Dopamine receptor D2L evaluated using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048299(CHEMBL335545 | 4-Phenyl-1-((R)-3-phenyl-cyclohex-3...)
Affinity DataKi:  26nMAssay Description:Tested for binding affinity towards human D2L receptor using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50048299(CHEMBL335545 | 4-Phenyl-1-((R)-3-phenyl-cyclohex-3...)
Affinity DataKi:  53nMAssay Description:Tested for binding affinity towards rat striatal D2 receptor using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048299(CHEMBL335545 | 4-Phenyl-1-((R)-3-phenyl-cyclohex-3...)
Affinity DataKi:  90.9nMAssay Description:Binding affinity towards human Dopamine receptor D4.2 evaluated using [3H]spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50048299(CHEMBL335545 | 4-Phenyl-1-((R)-3-phenyl-cyclohex-3...)
Affinity DataKi:  91nMAssay Description:Tested for binding affinity towards human Dopamine receptor D4.2 using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM50048299(CHEMBL335545 | 4-Phenyl-1-((R)-3-phenyl-cyclohex-3...)
Affinity DataKi: >1.00E+4nMAssay Description:Tested for binding affinity towards rat striatal dopamine receptor D1 using [3H]-SCH- 23390 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed