BDBM50159369 CGS-31,4447::CHEMBL415967::{1-[(S)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethylamino]-2-naphthalen-2-yl-ethyl}-phosphonic acid

SMILES OP(O)(=O)C(Cc1ccc2ccccc2c1)N[C@@H](Cc1ccc(cc1)-c1ccccc1)c1nnn[nH]1

InChI Key InChIKey=PIBUIEXHVFJHNQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50159369   

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50159369({1-[(S)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethyl...)
Affinity DataIC50: 45nMAssay Description:In vitro inhibition against recombinant human Endothelin converting enzyme 1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50159369({1-[(S)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethyl...)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of neutral endopeptidase 24.11(NEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetEndothelin-converting enzyme 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50159369({1-[(S)-2-Biphenyl-4-yl-1-(1H-tetrazol-5-yl)-ethyl...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration against human ECE-1 by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed