BDBM50006810 4-[4-(2,5-Dimethyl-pyrrol-1-yl)-phenyl]-but-3-enoic acid hydroxy-methyl-amide::CGS-22745::CHEMBL85509

SMILES CN(O)C(=O)C\C=C\c1ccc(cc1)-n1c(C)ccc1C

InChI Key InChIKey=YOQOHMWRJIMWLY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006810   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50006810(CHEMBL85509 | 4-[4-(2,5-Dimethyl-pyrrol-1-yl)-phen...)
Affinity DataIC50: 600nMAssay Description:The compound was tested for inhibitory activity against 5-Lipoxygenase in guinea pig polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2012
Entry Details Article
PubMed