BDBM50067081 9-Fluoro-2-furan-2-yl-5,6-dihydro-[1,2,4]triazolo[1,5-c]quinazolin-5-ylamine::9-Fluoro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylamine::CGS-15943::CHEMBL70605

SMILES Nc1nc2ccc(F)cc2c2nc(nn12)-c1ccco1

InChI Key InChIKey=KQBHEYASZHOLFC-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50067081   

TargetAdenosine receptor A2a(Rat)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50067081(9-Fluoro-2-furan-2-yl-5,6-dihydro-[1,2,4]triazolo[...)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]ZM-241385 binding in adenosine A2A receptor of rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50067081(9-Fluoro-2-furan-2-yl-5,6-dihydro-[1,2,4]triazolo[...)
Affinity DataKi:  7.90nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50067081(9-Fluoro-2-furan-2-yl-5,6-dihydro-[1,2,4]triazolo[...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50067081(9-Fluoro-2-furan-2-yl-5,6-dihydro-[1,2,4]triazolo[...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]DPCPX binding to adenosine A1 receptor of rat brain cortical membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50067081(9-Fluoro-2-furan-2-yl-5,6-dihydro-[1,2,4]triazolo[...)
Affinity DataKi:  140nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2012
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50067081(9-Fluoro-2-furan-2-yl-5,6-dihydro-[1,2,4]triazolo[...)
Affinity DataKi:  143nMAssay Description:Displacement of specific [125I]AB-MECA binding at human adenosine A3 receptor expressed in HEK 293 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50067081(9-Fluoro-2-furan-2-yl-5,6-dihydro-[1,2,4]triazolo[...)
Affinity DataKi:  143nMAssay Description:Binding affinity by its ability to displace [125I]AB-MECA from human adenosine A3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed