BDBM84957 CGS 9896::CHEMBL20042

SMILES Clc1ccc(cc1)-n1[nH]c2c(cnc3ccccc23)c1=O

InChI Key InChIKey=QCBUAKLOWCOUCR-UHFFFAOYSA-N

Data  6 KI  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 84957   

TargetGamma-aminobutyric acid receptor subunit alpha-1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM84957(CHEMBL20042 | CGS 9896)
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM84957(CHEMBL20042 | CGS 9896)
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]flumazenil from GABAA receptor subunit alpha-2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM84957(CHEMBL20042 | CGS 9896)
Affinity DataKd:  0.300nMAssay Description:Binding affinity to GABAA alpha-1-beta-2-gamma-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM84957(CHEMBL20042 | CGS 9896)
Affinity DataKd:  40nMAssay Description:Binding affinity to GABAA alpha-5-beta-2-gamma-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM84957(CHEMBL20042 | CGS 9896)
Affinity DataKi:  0.260nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2012
Entry Details Article
PubMed
LigandPNGBDBM84957(CHEMBL20042 | CGS 9896)
Affinity DataKi:  35.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
LigandPNGBDBM84957(CHEMBL20042 | CGS 9896)
Affinity DataKi:  59nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rat)
National Institute of Diabetes, Digestive and Kidney Diseases

Curated by PDSP Ki Database
LigandPNGBDBM84957(CHEMBL20042 | CGS 9896)
Affinity DataKi:  214nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
LigandPNGBDBM84957(CHEMBL20042 | CGS 9896)
Affinity DataKi:  285nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6(Rat)
National Institute of Diabetes, Digestive and Kidney Diseases

Curated by PDSP Ki Database
LigandPNGBDBM84957(CHEMBL20042 | CGS 9896)
Affinity DataKi:  500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed