BDBM14144 2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2-yl}-6-(cyclopentyloxy)benzen-1-olate::APC-10655::CA-06

SMILES NC(=[NH2+])c1ccc2nc([nH]c2c1)-c1cccc(OC2CCCC2)c1[O-]

InChI Key InChIKey=WCFWDBPDMBXMTQ-UHFFFAOYSA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 14144   

TargetSerine protease 1(Bovine)
Celera

LigandPNGBDBM14144(CA-06 | 2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  52nM ΔG°:  -9.83kcal/molepH: 7.67 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
LigandPNGBDBM14144(CA-06 | 2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  190nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2007
Entry Details Article
PubMed
LigandPNGBDBM14144(CA-06 | 2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  220nM ΔG°:  -8.98kcal/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2007
Entry Details Article
PubMed
LigandPNGBDBM14144(CA-06 | 2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  220nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Axys Pharmaceutical

LigandPNGBDBM14144(CA-06 | 2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  550nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2007
Entry Details Article
PubMed
TargetPlasminogen(Human)
Axys Pharmaceutical

LigandPNGBDBM14144(CA-06 | 2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  600nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Celera

LigandPNGBDBM14144(CA-06 | 2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  730nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Axys Pharmaceutical

LigandPNGBDBM14144(CA-06 | 2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  1.40E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Axys Pharmaceutical

LigandPNGBDBM14144(CA-06 | 2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  1.40E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
LigandPNGBDBM14144(CA-06 | 2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  4.40E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Axys Pharmaceutical

LigandPNGBDBM14144(CA-06 | 2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  1.50E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Axys Pharmaceutical

LigandPNGBDBM14144(CA-06 | 2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzo...)
Affinity DataKi:  1.50E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed