BDBM50639171 BGB-290::Bgb-290::Pamiparib

SMILES C[C@]12CCCN1CC1=NNC(=O)c3cc(F)cc4[nH]c2c1c34

InChI Key InChIKey=DENYZIUJOTUUNY-UHFFFAOYSA-N

Data  3 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50639171   

TargetPoly [ADP-ribose] polymerase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639171(Pamiparib | Bgb-290 | BGB-290)
Affinity DataIC50: 0.900nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50639171(Pamiparib | Bgb-290 | BGB-290)
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50639171(Pamiparib | Bgb-290 | BGB-290)
Affinity DataIC50: 0.920nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)