BDBM50088384 Barnidipine::Barnidipine HCl

SMILES COC(=O)C1=C(C)NC(C)=C([C@H]1c1cccc(c1)[N+]([O-])=O)C(=O)O[C@H]1CCN(Cc2ccccc2)C1

InChI Key InChIKey=VXMOONUMYLCFJD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50088384   

TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50088384(Barnidipine | Barnidipine HCl)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of L-type calcium channel measured using 2-electrode voltage-clamp in Xenopus oocyte heterologically expressing alpha-1C subunitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50088384(Barnidipine | Barnidipine HCl)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of L-type calcium channel measured using 2-electrode voltage-clamp in Xenopus oocyte heterologically expressing alpha-1C subunitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2016
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50088384(Barnidipine | Barnidipine HCl)
Affinity DataIC50: 1.26E+4nMAssay Description:TP_TRANSPORTER: inhibition of Digoxin transepithelial transport (basal to apical) (Digoxin: 0.1 uM) in MDR1-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed