BDBM50235800 Bambuterol::CHEBI:553827

SMILES CN(C)C(=O)Oc1cc(OC(=O)N(C)C)cc(c1)C(O)CNC(C)(C)C

InChI Key InChIKey=ANZXOIAKUNOVQU-UHFFFAOYSA-N

Data  12 IC50  2 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50235800   

TargetCholinesterase(Horse)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(CHEBI:553827 | Bambuterol)
Affinity DataKoff:  2.40E+3s-1Assay Description:Irreversible inhibition of equine serum BuChE assessed as second order carbamylation rate constant using S-butyrylthiocholine iodide as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(CHEBI:553827 | Bambuterol)
Affinity DataKoff:  1.30E+5s-1Assay Description:Irreversible inhibition of human plasma BuChE assessed as second order carbamylation rate constant using S-butyrylthiocholine iodide as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(CHEBI:553827 | Bambuterol)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human erythrocytes AChE using S-acetylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetCholinesterase(Horse)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(CHEBI:553827 | Bambuterol)
Affinity DataIC50: 119nMAssay Description:Inhibition of equine serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(CHEBI:553827 | Bambuterol)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of electric eel AChE using S-acetylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(CHEBI:553827 | Bambuterol)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human plasma BuChE using S-butyrylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(CHEBI:553827 | Bambuterol)
Affinity DataIC50: 3nMAssay Description:Inhibition of human blood BuChE using butyrylthiocholine as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(CHEBI:553827 | Bambuterol)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human blood AChE using acetylthiocholine as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2019
Entry Details Article
PubMed
TargetCholinesterase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(CHEBI:553827 | Bambuterol)
Affinity DataIC50: 3nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(CHEBI:553827 | Bambuterol)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(CHEBI:553827 | Bambuterol)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetCholinesterase(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50235800(CHEBI:553827 | Bambuterol)
Affinity DataIC50: 3nMAssay Description:Inhibition of BuchE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Rat)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50235800(CHEBI:553827 | Bambuterol)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of rat AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCarboxylic ester hydrolase(Rat)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50235800(CHEBI:553827 | Bambuterol)
Affinity DataIC50: 3nMAssay Description:Inhibition of rat BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed