BDBM50046268 6-Bromomethylene-3-naphthalen-1-yl-tetrahydro-pyran-2-one::6-[1-Bromo-meth-(E)-ylidene]-3-naphthalen-1-yl-tetrahydro-pyran-2-one::BTNP::CHEMBL6206

SMILES Br\C=C1/CCC(C(=O)O1)c1cccc2ccccc12

InChI Key InChIKey=BYUCSFWXCMTYOI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50046268   

Target85/88 kDa calcium-independent phospholipase A2(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50046268(6-[1-Bromo-meth-(E)-ylidene]-3-naphthalen-1-yl-tet...)
Affinity DataIC50: 140nMAssay Description:Compounds were evaluated for the inhibitory activity against canine myocardial cytosolic calcium dependent phospholipase A2. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50046268(6-[1-Bromo-meth-(E)-ylidene]-3-naphthalen-1-yl-tet...)
Affinity DataIC50: 800nMAssay Description:Irreversible inhibition of fatty acid amide hydrolaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50046268(6-[1-Bromo-meth-(E)-ylidene]-3-naphthalen-1-yl-tet...)
Affinity DataIC50: 800nMAssay Description:Inhibition of FAAH in rat brain assessed as hydrolysis of anandamideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
Target85/88 kDa calcium-independent phospholipase A2(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50046268(6-[1-Bromo-meth-(E)-ylidene]-3-naphthalen-1-yl-tet...)
Affinity DataIC50: 100nMAssay Description:Compounds were evaluated for the inhibitory activity against canine myocardial cytosolic calcium dependent phospholipase A2. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed