BDBM50049244 5-{4-[2-(Benzooxazol-2-yl-methyl-amino)-ethoxy]-benzyl}-thiazolidine-2,4-dione::BRL-48482::CHEMBL17805

SMILES CN(CCOc1ccc(Cc2sc(=O)[nH]c2O)cc1)c1nc2ccccc2o1

InChI Key InChIKey=YDFXQSJZFCAXMK-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50049244   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50049244(BRL-48482 | 5-{4-[2-(Benzooxazol-2-yl-methyl-amino...)
Affinity DataEC50:  11nMAssay Description:Activation of peroxisome proliferator activated receptor gamma measured by induction of 50% of maximum alkaline phosphatase activity, transfection as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Mouse)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50049244(BRL-48482 | 5-{4-[2-(Benzooxazol-2-yl-methyl-amino...)
Affinity DataEC50:  13nMAssay Description:In vitro transcriptional activation of Peroxisome proliferator activated receptor gamma (PPAR) expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50049244(BRL-48482 | 5-{4-[2-(Benzooxazol-2-yl-methyl-amino...)
Affinity DataKi:  22nMAssay Description:inhibition of [125I]SB 236636 binding to human PPAR gamma receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50049244(BRL-48482 | 5-{4-[2-(Benzooxazol-2-yl-methyl-amino...)
Affinity DataKi:  22nMAssay Description:Inhibition of [125I]SB 236636 binding to human PPAR gamma receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM50049244(BRL-48482 | 5-{4-[2-(Benzooxazol-2-yl-methyl-amino...)
Affinity DataKi:  27nMAssay Description:In vitro binding to peroxisome proliferator activated receptor gamma (PPAR gamma) using [3H]-BRL 49653 as radioligand in scintillation proximity assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2014
Entry Details Article
PubMed