BDBM50341914 1-[(n-Dodec-1-ylamino)ethyl]1,1-bisphosphonic acid::BPH-735::CHEMBL1765149

SMILES CCCCCCCCCCCCNCC(P(O)(O)=O)P(O)(O)=O

InChI Key InChIKey=MTPROXDBHCNBRU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50341914   

TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of California San Diego

LigandPNGBDBM50341914(1-[(n-Dodec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50: 3.70E+5nMpH: 7.5Assay Description:We screened an in-house library of 53 compounds using trans-FPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341914(1-[(n-Dodec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50: 811nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341914(1-[(n-Dodec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50: 93nMAssay Description:Inhibition of Toxoplasma gondii FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetSolanesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341914(1-[(n-Dodec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50: 3.18E+3nMAssay Description:Inhibition of Trypanosoma cruzi SPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341914(1-[(n-Dodec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50: 810nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341914(1-[(n-Dodec-1-ylamino)ethyl]1,1-bisphosphonic acid...)
Affinity DataIC50: 93nMAssay Description:Inhibition of Toxoplasma gondii FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed