BDBM50173768 (biphenyl-3-yl-hydroxy-phosphono-methyl)-phosphonic acid::BPH-306::CHEMBL196676

SMILES OC(c1cccc(c1)-c1ccccc1)(P(O)(O)=O)P(O)(O)=O

InChI Key InChIKey=DUFXFUIMHWDTGA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50173768   

TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of California San Diego

LigandPNGBDBM50173768((biphenyl-3-yl-hydroxy-phosphono-methyl)-phosphoni...)
Affinity DataIC50: 4.00E+4nMpH: 7.5Assay Description:We screened an in-house library of 53 compounds using trans-FPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details Article
PubMed
TargetPhosphotransferase(Trypanosoma cruzi)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50173768((biphenyl-3-yl-hydroxy-phosphono-methyl)-phosphoni...)
Affinity DataIC50: 3.47E+4nMAssay Description:Inhibitory activity against Trypanosoma cruzi hexokinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetH(+)-exporting diphosphatase(Trypanosoma brucei)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50173768((biphenyl-3-yl-hydroxy-phosphono-methyl)-phosphoni...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei soluble vacuolar pyrophosphatase expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetPhosphotransferase(Trypanosoma cruzi)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50173768((biphenyl-3-yl-hydroxy-phosphono-methyl)-phosphoni...)
Affinity DataIC50: 810nMAssay Description:Inhibition of Trypanosoma cruzi hexokinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed