BDBM97434 100873, 18::BPH-1375

SMILES NC(=O)c1cc(NC(=O)c2ccc(cc2)C(=O)Nc2cc(cc(c2)C2=NCCN2)C(N)=O)cc(c1)C1=NCCN1

InChI Key InChIKey=FNXIZGCMHLSQBQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 97434   

TargetFarnesyl pyrophosphate synthase(Human)
University of California San Diego

LigandPNGBDBM97434(100873, 18 | BPH-1375)
Affinity DataIC50: 1.07E+4nMpH: 7.4 T: 2°CAssay Description:Human FPPS was expressed and purified and inhibition assays carried out as described previously.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2013
Entry Details Article
PubMed
TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of California San Diego

LigandPNGBDBM97434(100873, 18 | BPH-1375)
Affinity DataIC50: 8.40E+3nMpH: 7.5Assay Description:We screened an in-house library of 43 compounds using GPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by DPPS w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details Article
PubMed