BDBM97430 50460, 14::BPH-1358

SMILES O=C(Nc1cccc(c1)C1=NCCN1)c1ccc(cc1)-c1ccc(cc1)C(=O)Nc1cccc(c1)C1=NCCN1

InChI Key InChIKey=HOYOJUMMRGKESB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 97430   

TargetFarnesyl pyrophosphate synthase(Human)
University of California San Diego

LigandPNGBDBM97430(50460, 14 | BPH-1358)
Affinity DataIC50: 1.80E+3nMpH: 7.4 T: 2°CAssay Description:Human FPPS was expressed and purified and inhibition assays carried out as described previously.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2013
Entry Details Article
PubMed
TargetTuberculosinyl adenosine transferase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of California San Diego

LigandPNGBDBM97430(50460, 14 | BPH-1358)
Affinity DataIC50: 9.60E+4nMAssay Description:For inhibition assay of Rv3378c, using tuberculosinyl diphosphate and adenosine as substrates, a mixture of 100 µM TPP, 100 µM adenosine,75 µg/mL Rv3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of California San Diego

LigandPNGBDBM97430(50460, 14 | BPH-1358)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human FPPS pre-incubated for 30 mins using GPP and IPP by continuous spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2016
Entry Details Article
PubMed