BDBM102620 BMX-IN-1::N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[h][1,::US10000483, Compound I-14
SMILES Cc1ccc(cc1NC(=O)C=C)-n1c2c(ccc1=O)cnc1ccc(cc21)-c1ccc(NS(C)(=O)=O)cc1
InChI Key InChIKey=SFMJNHNUOVADRW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 21 hits for monomerid = 102620
Affinity DataIC50: 8nMAssay Description:DiscoverX binding assays were performed according to published methods (Fabian et al., Nat. Biotechnol. 23, 329-36 (2005); Davis et al., Nat. Biotech...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant full length His-tagged human BTK expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate preincub...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 175nMAssay Description:Inhibition of recombinant GST-tagged human JAK3 expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate preincubated for 1 ...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Blk(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 377nMAssay Description:Inhibition of recombinant full length His-tagged human BLK expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate preincub...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant full length His-tagged human BMX expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as substrate preincub...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 175nMAssay Description:DiscoverX binding assays were performed according to published methods (Fabian et al., Nat. Biotechnol. 23, 329-36 (2005); Davis et al., Nat. Biotech...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:DiscoverX binding assays were performed according to published methods (Fabian et al., Nat. Biotechnol. 23, 329-36 (2005); Davis et al., Nat. Biotech...More data for this Ligand-Target Pair
Affinity DataIC50: 653nMAssay Description:DiscoverX binding assays were performed according to published methods (Fabian et al., Nat. Biotechnol. 23, 329-36 (2005); Davis et al., Nat. Biotech...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Blk(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 377nMAssay Description:DiscoverX binding assays were performed according to published methods (Fabian et al., Nat. Biotechnol. 23, 329-36 (2005); Davis et al., Nat. Biotech...More data for this Ligand-Target Pair
Affinity DataIC50: 325nMAssay Description:DiscoverX binding assays were performed according to published methods (Fabian et al., Nat. Biotechnol. 23, 329-36 (2005); Davis et al., Nat. Biotech...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Blk(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
TargetTyrosine-protein kinase BTK(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:DiscoverX binding assays were performed according to published methods (Fabian et al., Nat. Biotechnol. 23, 329-36 (2005); Davis et al., Nat. Biotech...More data for this Ligand-Target Pair
Affinity DataIC50: 7.99nMAssay Description:Purified BMX was mixed with substrate (FAK or Bmxtides), kinase buffer (final 20 mM HEPES, pH 7.5, 10 mM MgCl2, 20 mM β-glycerophosphate, 1 mM d...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of full-length recombinant human His-tagged BTK expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
TargetTyrosine-protein kinase BTK(Human)
University of Science and Technology of China
Curated by ChEMBL
University of Science and Technology of China
Curated by ChEMBL
Affinity DataKi: 3.20nMAssay Description:Irreversible inhibition of recombinant full length His-tagged human BTK expressed in baculovirus expression system using poly (4:1 Glu, Tyr) as subst...More data for this Ligand-Target Pair