BDBM50107438 (S)-1-[(S)-3-Hydroxy-2-(naphthalene-2-sulfonylamino)-propionyl]-pyrrolidine-2-carboxylic acid (4-guanidino-butyl)-amide::BMS-185367::CHEMBL136082

SMILES NC(=N)NCCCCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NS(=O)(=O)c1ccc2ccccc2c1

InChI Key InChIKey=MHSALEQAXYJWDB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107438   

TargetProthrombin(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107438((S)-1-[(S)-3-Hydroxy-2-(naphthalene-2-sulfonylamin...)
Affinity DataIC50: 2.80E+3nMAssay Description:In vitro inhibition of thrombin catalytic activity using s-2238 substrate at 10 uM was measured at rt after 3 min incubation with compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50107438((S)-1-[(S)-3-Hydroxy-2-(naphthalene-2-sulfonylamin...)
Affinity DataIC50: 2.80E+3nMAssay Description:In vitro inhibitory activity against hydrolysis of thrombin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed