BDBM50222414 BML-210::CHEBI:61077::CHEMBL324053

SMILES Nc1ccccc1NC(=O)CCCCCCC(=O)Nc1ccccc1

InChI Key InChIKey=RFLHBLWLFUFFDZ-UHFFFAOYSA-N

Data  30 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 30 hits for monomerid = 50222414   

TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 944nMAssay Description:Inhibition of HDAC1 (unknown origin) preincubated for 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 463nMAssay Description:Inhibition of HDAC3 (unknown origin) preincubated for 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 391nMAssay Description:Inhibition of HDAC3 (unknown origin) preincubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 535nMAssay Description:Inhibition of HDAC3 (unknown origin) preincubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 559nMAssay Description:Inhibition of HDAC3 (unknown origin) preincubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 659nMAssay Description:Inhibition of HDAC3 (unknown origin) preincubated for 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) preincubated for 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) preincubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) preincubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) preincubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) preincubated for 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) preincubated for 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) preincubated for 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) preincubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 910nMAssay Description:Inhibition of HDAC1 (unknown origin) preincubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 1.20E+5nMAssay Description:In vitro inhibitory activity against histone deacetylase (HDAC) isolated from HeLa nuclear extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2018
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 9(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 379nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 530nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 828nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 8.70E+4nMAssay Description:Inhibition of HDAC in human HeLa cell extract by fluorescence plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50222414(CHEMBL324053 | CHEBI:61077 | BML-210)
Affinity DataIC50: 1.20E+5nMAssay Description:In vitro inhibitory activity against human histone deacetylase (HDAC) using HeLa nuclear extractMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2018
Entry Details Article
PubMed