BDBM36489 BI-12H11

SMILES CN1SC(=C)c2cc(ccc12)S(=O)(=O)Nc1ccccc1N1CCCCC1

InChI Key InChIKey=CUFAPPAMEQXCPX-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 36489   

TargetMitogen-activated protein kinase 14(Human)
Burnham Institute For Medical Research

LigandPNGBDBM36489(BI-12H11)
Affinity DataIC50: 710nM Kd:  760nMpH: 7.0Assay Description:In vitro kinase activity and selectivity was determined by using SelectScreen kinase profiling Z'-LYTE assay from Invitrogen.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Burnham Institute For Medical Research

LigandPNGBDBM36489(BI-12H11)
Affinity DataIC50: 5.61E+3nMpH: 7.0Assay Description:The competitive binding between test compounds and a fluorescence p38 alpha inhibitor, SK&F 86002. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2011
Entry Details Article
PubMed