BDBM50021153 1H-1-Benzazepine-1-acetic acid, 3-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-2,3,4,5-tetrahydro-2-oxo-, (S-(R*,R*))-::BENAZEPRIL::CHEMBL838::[(3S)-3-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid

SMILES CCOC(=O)[C@H](CCc1ccccc1)N[C@H]1CCc2ccccc2N(CC(O)=O)C1=O

InChI Key InChIKey=XPCFTKFZXHTYIP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50021153   

TargetAngiotensin-converting enzyme(Rabbit)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50021153([(3S)-3-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]a...)
Affinity DataIC50: 212nMAssay Description:Inhibition of rabbit lung ACE assessed as hydrolysis of hippuryl-histidyl-leucine to hippuric acid and histidyl-leucine after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50021153([(3S)-3-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]a...)
Affinity DataIC50: 2nMAssay Description:Tested for 50% inhibition of Angiotensin converting enzyme(ACE) obtained from rabbit lung (in vitro)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rabbit)
Csir-Indian Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50021153([(3S)-3-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]a...)
Affinity DataIC50: 100nMAssay Description:Inhibition of rabbit lung ACE assessed as hippuryl-histidyl-leucine hydrolysis after 30 mins by colorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2016
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50021153([(3S)-3-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]a...)
Affinity DataIC50: 1.70nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50021153([(3S)-3-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]a...)
Affinity DataIC50: 1.70nMAssay Description:Inhibitory activity against angiotensin I converting enzyme (ACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed