BDBM99920 CHEMBL1945133::US8501991, 7

SMILES CN(C)CCCCCCCC(=O)Nc1ccc(NC(=S)NC(=O)c2ccc(cc2)C(C)(C)C)cc1

InChI Key InChIKey=UEMLCCZQJPRXQW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 99920   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University Court of The University of Dundee

US Patent
LigandPNGBDBM99920(CHEMBL1945133 | US8501991, 7)
Affinity DataIC50: 2.50E+4nMAssay Description:SIRT1 inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
Go to US Patent

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University Court of The University of Dundee

US Patent
LigandPNGBDBM99920(CHEMBL1945133 | US8501991, 7)
Affinity DataIC50: 2.47E+4nMAssay Description:Inhibition of recombinant human SitT1 by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

Curated by ChEMBL
LigandPNGBDBM99920(CHEMBL1945133 | US8501991, 7)
Affinity DataIC50: 4.17E+4nMAssay Description:Inhibition of recombinant human SitT2 by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed