BDBM99892 US8501936, 411

SMILES CCN1CCP(=O)(CC1)c1ccc(Nc2nc3c(cccn3n2)-c2ccc(cc2)S(C)(=O)=O)cc1

InChI Key InChIKey=BFEMVAYKIVOLEV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 99892   

TargetFocal adhesion kinase 1(Human)
Cephalon

US Patent
LigandPNGBDBM99892(US8501936, 411)
Affinity DataIC50: 1.86E+3nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
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TargetTyrosine-protein kinase JAK2(Human)
Cephalon

US Patent
LigandPNGBDBM99892(US8501936, 411)
Affinity DataIC50: 1.62nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3(Human)
Cephalon

US Patent
LigandPNGBDBM99892(US8501936, 411)
Affinity DataIC50: 57.9nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
Go to US Patent