BDBM99459 US8497281, 237

SMILES Cc1nc2cc3C[C@H]4[C@H](CCCN4C(=O)c4ccc5nc[nH]c5c4)c3cc2o1

InChI Key InChIKey=FGANXIQPUHEMEK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99459   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM99459(US8497281, 237)
Affinity DataIC50: 248nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2013
Entry Details
Go to US Patent