BDBM99437 US8497281, 215

SMILES O=C(N1CCC[C@H]2[C@@H]1Cc1cc(ccc21)C#N)c1ccc2nc[nH]c2c1

InChI Key InChIKey=AQRSRWQZGJYGAF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99437   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM99437(US8497281, 215)
Affinity DataIC50: 214nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2013
Entry Details
Go to US Patent