BDBM99435 US8497281, 213

SMILES C[C@H]1CCN([C@H]2Cc3ccccc3[C@@H]12)C(=O)c1ccc2nc[nH]c2c1

InChI Key InChIKey=BRUKCJCBSLIOTE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 99435   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM99435(US8497281, 213)
Affinity DataIC50: 55nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2013
Entry Details
Go to US Patent