BDBM98992 US8497265, 448

SMILES C1C(CN1c1ccc2ccccc2n1)Oc1nccnc1-c1ccc2scnc2c1

InChI Key InChIKey=RFCZNMOBMVGUBS-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 98992   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Amgen

US Patent

LigandBDBM98992(US8497265, 448)Copy SMILESCopy InChI

Affinity DataIC50: 307nMAssay Description:Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif). More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/9/2013
Entry Details
Copy Entry DOIGo to US Patent

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TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
TBA

Curated by ChEMBL

LigandBDBM98992(US8497265, 448)Copy SMILESCopy InChI

Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of human PDE10A using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/16/2016
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL