BDBM98735 US8487093, 80

SMILES OS(=O)(=O)ON1[C@H]2CN([C@@H](CC2)C(=O)N[C@@H]2CCCNCC2)C1=O

InChI Key InChIKey=BIJYWYKVNVASSF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 98735   

TargetBeta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM98735(US8487093, 80)
Affinity DataIC50: 225nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2013
Entry Details
Go to US Patent

TargetBeta-lactamase(Pseudomonas aeruginosa)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM98735(US8487093, 80)
Affinity DataIC50: 520nMAssay Description:Enzyme activities were measured in the presence of the test inhibitor in spectrophotometric assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2013
Entry Details
Go to US Patent

TargetOxa40(Acinetobacter baumannii)
Merck Research Labs

Curated by ChEMBL
LigandPNGBDBM98735(US8487093, 80)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of beta-lactamase Oxa40 in Acinetobacter baumannii assessed as inhibition of hydrolysis of nitrocefinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed