BDBM98635 US8497376, 16

SMILES CC1(C)CC(CC(C)(C)O1)c1ccc(NC(=O)c2ncc([nH]2)C#N)c(n1)C1=CCCCC1

InChI Key InChIKey=HHNLZUJUHWLYCI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98635   

TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM98635(US8497376, 16)
Affinity DataIC50: 1.40nMpH: 7.5Assay Description:An autophosphorylation, fluroescence polarization competition immunoassay was used to determine the potency for c-fms inhibition.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2013
Entry Details
Go to US Patent